Stuyt, Q.A.J.M. (Quirijn) (2017) The predictive value of disease severity indices in quality of sleep in critically ill A prospective observational study to evaluate the influence of disease severity on sleep disturbance in critically ill patients. thesis, Medicine.
Full text available on request.Abstract
Background: Sleep is known to be severely disturbed in patients in the Intensive Care Unit (ICU). Sleep deprivation has major consequences on human physiology and the recovery process. Individual factors, whether they are environmental or patient related, do not account for the entire sleep disturbance seen in ICU patients, even when these factors are combined. The aim of this study is to investigate the aggregated contribution of ‘disease severity’ as defined by several often used disease severity scales or indices to quality of sleep. Methods: All patients were screened for eligibility upon ICU admission. When a patient met the criteria, a polysomnography (PSG) was performed for at least 24 hours to asses total sleep time (TST), sleep fragmentation, daytime sleep and distribution in sleep stages. Light, noise and temperature levels were recorded during registration. Clinical data was retrieved from the patient’s record. Disease severity scores were calculated per registration day or upon admission. Results: A total of 42 patients were included. All patients demonstrated abnormal sleep architecture. Disease severity scores were positively correlated to daytime sleep. Sleep architecture did not differ between daytime and nighttime. Surgical patients and patients receiving propofol had a higher TST. Length of stay in the hospital or ICU was positively correlated to N1 sleep and negatively correlated to N3 sleep. Conclusion: This observational study showed that sleep is strongly disturbed in all the observed critically ill patients, regardless of ICU admission criteria or disease severity. Disease severity scores have a limited predictive value regarding to sleep disturbance. The length of admission seemed to result in a shift from deeper sleep stages to lighter sleep stages.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Supervisors and Tulleken, Prof. dr. J.E MD and Reinke, L MSc and Department of Critical Care, University Medical Center Groni |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:56 |
| Last Modified: | 25 Jun 2020 10:56 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1666 |
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