Jongkind, C.S (Cyrielle Stephanie) (2010) Welke soort fluoride in tandpasta biedt de beste bescherming tegen caries?Biedt natriumfluoride in vergelijking met tinfluoride, natriummonofluorfosfaat of aminfluoride de beste bescherming tegen caries? thesis, Dentistry.
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Abstract
Fluoride can, including by promoting remineralization, protect the dentition against caries. The caries preventive effect of fluoride has been known for over 90 years. Nowadays, toothpaste is world most widely used method of delivering fluoride. By producing a fluoride toothpaste different types of fluoride can be used. In the Netherlands fluoride toothpastes contain sodium fluoride, stannous fluoride, sodium monofluorphosphate or amine fluoride. Worldwide, the most commonly used type of fluoride is sodium fluoride. Purpose of the literature review is to determine if in toothpaste sodium fluoride is the best protection against caries compared to stannous fluoride, sodium monofluorphosphate or amine fluoride. Three search terms results on PubMed in 111 articles, on Cochrane Library in 17 articles. After applying in- and exclusion criteria and analysis by the Cochrane Collaboration review list 6 articles were used for the literature review. The 6 studies involved investigations that all enrolled, different types of fluoride, in a different way. There are discrepancies in the measurement methods, the types of fluoride toothpastes and the types of surfaces and caries lesions. The effectiveness of different fluoride toothpastes are examined and compared. Significant less caries lesions have been demonstrated clinically when using a high concentration of sodium fluoride (2800 ppm F) compared to a control sodium fluoride ( 11 00 ppm F). Sodium fluoride in situ shows better results compared to sodium monofluorphosphate and stannous fluoride, in partially demineralized enamel was a higher absorption of fluoride observed. The results of amine fluoride, amine- with stannous fluoride and stannous fluoride with sodium monofluorphosphate differed hardly from sodium fluoride. On long-existing white spot lesions clinically there was no significant difference demonstrated between sodium fluoride and amine fluoride. With respect to root caries lesions there was no significant difference demonstrated between sodium fluoride and amine- with stannous fluoride. Stannous fluoride with sodium hexametaphosphate (1100 ppm F) showed significantly fewer caries lesions compared to sodium fluoride (1100 ppm F) and showed less demineralization of smooth root surface compared to sodium fluoride- and a placebo toothpaste. Sodium fluoride offers in situ a better protection against caries compared to monofluorphosphate and stannous fluoride. Clinically, there is no significant difference demonstrated between sodium fluoride and amine fluoride.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Blanksma, Mevr. dr. N.G. and Faculteit Medische Wetenschappen/UMCG and Centrum voor Tandheelkunde en Mondzorgkunde |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:56 |
| Last Modified: | 25 Jun 2020 10:56 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1658 |
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