Hofstede, S. (Stéphanie) (2019) Predictive clinical characteristics of patients with transtibial amputation converted to transfemoral amputation: An explorative retrospective study. thesis, Medicine.
Full text available on request.Abstract
Introduction: much is known about predictive variables and characteristics of patients with transtibial amputation (TTA) or transfemoral amputation (TFA).1-5 There is lack of knowledge about the group converted from TTA to TFA.6 Aim of this study was to compare predictive characteristics of patients with TTA, TFA and TTA converted to TFA. Method: between January 2011 and December 2017 retrospective data was retrieved from (medical) records from Isala. Beside descriptive statistics, differences between groups were tested with the Independent Samples T-, Mann-Whitney U- and Chi-Square Test. Multiple logistic regression- and survival analysis were performed. Results: 383 patients were included (288 TTA; 95 TFA). After TTA, 16.9%, was converted to TFA. Patients with DM were three times more likely to have TTA compared to TTA converted to TFA. TFA patients (total group) have a higher mortality risk compared to TTA (total group) (HR 1.5). Predictive factors for mortality are: - in TTA (total group) 72-92 years (HR 1.5) and congestive heart failure (CHF) (HR 2.0) - in TFA (total group) 72-92 years (HR 2.0) and dialysis (HR 3.1) - in TTA alone CHF (HR 2.1) - in TTA converted to TFA female gender (HR 19.0) and dialysis (HR 101.2) Conclusion: this study showed patients with DM were more likely to have TTA compared to TTA converted to TFA. TFA, age, CHF, dialysis and female gender are predictive factors for mortality. This is in comparison with literature and can be used for patient-specific choices regarding amputation level
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Winter, Drs. R.E. |
| Supervisor name: | Local supervisor: and Winter, Drs. R.E. & and Brink, S.M. and Discipline group: and Rehabilitation medicine and Isala Zwolle, the Netherlands |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:56 |
| Last Modified: | 25 Jun 2020 10:56 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1619 |
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