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Faculty of Medical Sciences

Maxillary sinus floor elevation with autogenous bone, bone substitutes and growth factors :A systematic review

Rickert, D. (Danielle) (2009) Maxillary sinus floor elevation with autogenous bone, bone substitutes and growth factors :A systematic review. thesis, Dentistry.

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Abstract

Abstract Aim: This study systematically reviewed the literature regarding the treatment outcome of maxillary sinus floor elevation procedures used to create a sufficient bone volume to enable reliable implant placement. Sinus floor evaluations assessed were performed with autogenous bone, autogenous bone in combination with growth factors or bone substitutes, or solely bone substitutes. The primary objective of this systematic review was to assess the histomorphometric bone volume and implant survival rate after sinus floor elevation surgery, based on (randomized) clinical trails from 1979 to July 2008, and to determine whether the bone volume is affected by the grafting material or growth factor applied. Material and Methods: For this systematic review, a thorough search of the literature was conducted in electronic databases of MEDLINE (1979-July 2008) (via PUBMED). The search strategy used was a combination of MeSH terms and free text words. Two reviewers independently assessed the methodological quality of the various articles. Results: Out of 38 primarily selected articles, 9 studies fulfilled all inclusion criteria. Meta-analysis showed that the overall bone volume 5 months after treatment was 40.6% for the control group (autologous bone) and 38.2% for the test groups (bone substitutes, growth factors or a combination with autogenous bone). After analysis of all histomorphomertic results it was obvious that the bone volume after five months of healing time was irrespective of the grafting materials analyzed in this systematic review of the literature. Conclusion: This systematic review indicates that the use bovine hydroxyapatite (BioOss ®), or B-tricalcium phosphate (Cerasorb®) are acceptable alternatives to the use of autogenous bone alone, thus decreasing both the amount of autogenous bone required and the accompanying donor site morbidity. Grafts using bone-substitute materials were as effective as those using particulate autogenous bone, either when used alone or mixed with autogenous bone. The one-year overall implant survival rate from these studies was 96.2% for the control group treated with autogenous bone alone and 96.0% for the test group.

Item Type: Thesis (Thesis)
Supervisor name: Begeleiders: and Raghoebar, Prof. Dr. G.M. and Vissink, Prof. Dr. A. and Disciplinegroep: Mondziekten en Kaakchirurgie, UMCG
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:55
Last Modified: 25 Jun 2020 10:55
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/1618

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