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Faculty of Medical Sciences

Het effect van xylitol op preventie van tandcaries:een systematisch literatuuroverzicht

Bhagoe, S. (2010) Het effect van xylitol op preventie van tandcaries:een systematisch literatuuroverzicht. thesis, Dentistry.

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Abstract

Caries is still a common disease among children and adults. Sometimes preventive means fail to improve oral health. Products containing xylitol have been advanced as a significant alternative treatment for caries active patients. Xylitol is a naturallyoccurring sugar alcohol and is part of the sugar alcohols (polyols). Although there is evidence that xylitol is non-cariogenic, there is some scepticism about its cariostatic nature. There are several different mechanisms proposed by which xylitol oral products might work. The aim of this systematic review is to help clarify how effective this proposed treatment is. Criteria for considering studies were established before searching. The search was conducted in the following databases: Medline, Embase en The Cochrane Library (Central Register of Controlled Trials) and hand searching through journals was done. After selection six articles were used for data collection and quality assessment. It was decided not to perform meta-analysis because of insufficient comparability of the studies; difference in xylitol intervention, control groups, methods of caries diagnosis, etc. The most important results are that there is a significant caries reduction when using xylitol containing products compared to using nothing and that there's no difference in caries prevalence between xylitol gum users and control gum users. This means that it is unclear whether the caries inhibitory effect of xylitol containing products is caused by the presence of xylitol in these products. Conclusion: there's not enough evidence to support the use of xylitol as preventive treatment. More research is needed to learn more about this topic.

Item Type: Thesis (Thesis)
Supervisor name: Begeleider: ` and Huddleston Slater, J.R.R.
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:55
Last Modified: 25 Jun 2020 10:55
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/1554

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