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Faculty of Medical Sciences

Health problems in colorectal cancer survivors.

Kruijer, M. (Margreet) (2014) Health problems in colorectal cancer survivors. thesis, Medicine.

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Abstract

Background: To investigate the health problems in survivors of cancer and to enable the use of the International Classification of Functioning, Disability and Health (ICF) in clinical practice, core sets have been developed. Aim: The purpose of this study was to describe the most relevant health problems experienced by 1) colorectal cancer survivors and 2) colorectal-, or breast-, or lung cancer survivors, more than one year post diagnosis, by means of clinically relevant ICF categories. Methods: To reach consensus (agreement) on the most relevant health problems, a Delphi study was performed with medical and non-medical experts, and experts by experience, in the field of colorectal cancer. Experts had a transcending view on colorectal cancer survivors, more than one year post diagnosis. In two Delphi rounds, the experts completed a questionnaire containing ICF categories. The first Delphi round consisted of all 265 ICF categories on three-numbered level of abstraction, and was designed to identify the degree of relevance of each category. In the second Delphi round, experts received the ‘highly relevant’ and ‘relevant’ categories from the first Delphi round, and reached consensus on the definite list of ICF categories reflecting the most relevant health problems in colorectal cancer survivors. Communication proceeded entirely electronic, and experts filled in the questionnaire separately from each other. Two other students executed the same study with breast-, and lung cancer experts. The opinions of the three expert panels were combined after each round to generate overall consensus. Results: The first Delphi round consisted of 28 colorectal cancer experts, who rated 22 categories as ‘highly relevant’ and 145 categories as ‘relevant’. The second round was carried out by 21 of these 28 experts (response rate 75%), who identified 22 clinically relevant categories: five on Body Functions, zero on Body Structures, eleven on Activities and Participation and six on Environmental Factors. The combined panel of colorectal-, breast-, and lung cancer consisted of 76 experts, who constructed a list of 26 clinically relevant ICF categories: six on Body Functions, zero on Body Structures, thirteen on Activities and Participation and seven on Environmental Factors. Conclusion: This study presented two ICF category lists: one for colorectal cancer survivors, and one for colorectal-, or breast-, or lung cancer survivors, both more than one year post diagnosis. Both lists are a specific and fast instrument to assess the health problems in the reviewed cancer survivors, more than one year post diagnosis. The knowledge of these clinically relevant issues adds up to the existing literature and can be useful in clinical practice as screening instrument in the follow-up of colorectal-, or breast-, or lung cancer survivors. Implications: Further validation and evaluation is necessary to be able to use the here presented lists in clinical practice.

Item Type: Thesis (Thesis)
Supervisor name: Wynia, Dr. K. and Berendsen, Dr. A.J.
Faculty: Medical Sciences
Date Deposited: 25 Jun 2020 10:54
Last Modified: 25 Jun 2020 10:54
URI: https://umcg.studenttheses.ub.rug.nl/id/eprint/1468

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