Ante, M. (Marius) (2015) Long-term results after thoracic endovascular aortic repair in patients with thoracic and thoracoabdominal aortic aneurysms. thesis, Medicine.
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Abstract
Objectives: To report long-term results after thoracic endovascular aortic repair (TEVAR) in thoracic aortic aneurysms (TAA) and thoracoabdominal aortic aneurysms (TAAA). Methods: Between 1997 and May 2010, 269 patients were treated with TEVAR, in 100 cases for aneurysmal disease (72 male, mean age 68.3 yrs). Retrospective analysis is performed from a prospectively maintained database with a complete 5-year follow-up (FU) (mean 56.73 mths). 49 patients were admitted with an intact TAA (iTAA), 25 with a ruptured TAA or TAAA (rTAA), 18 with an intact TAAA (iTAAA) and 8 with an intact, posttraumatic TAA (pTAA). Primary endpoints are 5-year all-cause and TEVAR-related mortality. Secondary endpoints are causes of death, complication- and reintervention rates. Results: Overall 5-year mortality rate was 50% and respectively 40.8% in iTAA, 80% in rTAA, 12.5% in pTAA and 50% in iTAAA. Overall procedure related mortality was 21%, 10.2% in iTAA (n=5), 40% in rTAA (n=10), 33% in iTAAA (n=6) and 0 in pTAA. Freedom from complication was 52%, 47.2% and 47.2% at 1, 3 and 5 years respectively. Endoleak rate was 17%, paraplegia rate 2%, incidence of secondary aortobronchial fistula 2% and aortoesophageal fistula 2%. Freedom from reintervention was 82%, 77.8% and 71.2% at 1, 3 and 5 years. Conclusions: Long-term results after TEVAR for aneurysmatic aortic disease show relevant overall and procedure related mortality in both, elective and urgent indications. Complications and reinterventions occur even as late events and emphasize the necessity for long-term FU.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Keller, Dr. med. B.P.J.A. |
| Supervisor name: | Local supervisor: and Böckler, Prof. Dr. med. D. and University Hospital Heidelberg, Department of Vascular and E |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:52 |
| Last Modified: | 25 Jun 2020 10:52 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1294 |
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