Sjoerdsma, M.H. (2013) Longgeluiden en RSV bronchiolitis. Digitale analyse van longgeluiden en ademhaling voor en na het vernevelen van hypertoon zout bij kinderen met een RSV bronchiolitis. thesis, Medicine.
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Abstract
Introduction: Acute respiratory syncytial virus bronchiolitis is the most common cause of lower respiratory infections in infants and young children and the leading cause of admission in infants younger than one year. Recent studies show a positive effect of nebulization with hypertonic saline. Nebulization with hypertonic saline resulted in a shorter mean length of hospital stay and a lower clinical respiratory score. Nevertheless the immediate effect of nebuliztion with hypertonic saline on lung sounds and breathingpattern has never been studied. In this study, the immediate effect of nebulization with hypertonic saline will be evaluated by analyzing the lungsounds and breathingpattern before and after nebulization. Materials and method: It was an observational pilot study. Children from 0-36 months, admitted with RSV bronchiolitis were included. Lungsounds and breathing patterns were registered with the PulmoTrack®, before and fifteen minutes after nebulization with hypertonic saline. Also the validated clinical respiratory score, (RDAI-score) and the clinical and demographic data were registered for every patient. Results: The lungsounds and breathing patterns of 27 patients with RSV bronchiolitis were analyzed before and after nebulization with hypertonic saline. There was no significant decrease of percentage of wheeze and no change in I/E ratio. However there was a trend in a decrease in percentage of wheezing after a single nebulization with hypertonic saline. There was a significant increase in episodes of coughing. There was a positive correlation between the percentage of wheezing before nebulization and the decrease in percentage of wheezing after nebulization. Conclusion: A single nebulization with hypertonic saline in patients with RSV bronchiolitis showed no significant decrease of percentage wheeze and had no significant effect on the expiration time.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Kamps, Dr. A.W.A. and Faber, Drs. T.E. and Medisch Centrum Leeuwarden and Afdeling Kindergeneeskunde |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:51 |
| Last Modified: | 25 Jun 2020 10:51 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1203 |
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