Kruth, O. (2018) Influence of hypoxia on cognitive deficits and everyday-life skills in geriatric patients. thesis, Medicine.
Full text available on request.Abstract
Patients with an age of 75 years or older were tested cognitively by the “Alterskonzentrationstest” (AKT). Furthermore, patients had a polygraphic examination to test for nocturnal hypoxia, apneas and hypopneas. Correlation analysis was carried out between the parameters T90 (time of < 90% saturation) and AHI (Apnea-Hypopnea Index) and the results of the AKT. Furthermore, a t-test for independent samples was carried out between the groups with a pathologic and non-pathologic T90 / AHI score. In addition, data from the Geriatric Assessment was taken into account. Results: 40 patients were recruited within their in-patient stay. We found no significant correlations between T90 and AHI and the results from the AKT. The results from the t-tests were not significant either, but showed tendencies assuming the pathologic groups performed poorer in different functions. Additionally, patients with a higher level in T90 and AHI seemed to have worse outcome in the Geriatric Assessment. Discussion & Conclusion: It can be assumed that patients with a higher T90 and AHI are cognitively and physically more impaired and are more multimorbid. It has to be respected that not the hypoxia alone leads to impairment in cognitive function but rather the combination of hypoxia and the breathing disorder. Due to the small sample size of 40 patients further research should be done to prove the associations between the two parameters and cognitive performance.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Faculty supervisor: and Jong, Dr. B. M. de and Universitair Medisch Centrum Groningen |
| Supervisor name: | Second supervisor: and Kotterba, Prof. Dr. med. Sylvia and Klinikum Leer, Germany |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:50 |
| Last Modified: | 25 Jun 2020 10:50 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1138 |
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