Derks, Eveline Anne-Jet (2012) Breast Reconstruction after Mastectomy: Evaluation of postoperative Quality of Life after mastectomy. thesis, Medicine.
Full text available on request.Abstract
Introduction: Consensus is that breast reconstruction after mastectomy positively influences the Quality of Life (QoL) of breast cancer patients compared to mastectomy alone. However, the results of previous studies are not conclusive. Therefore I evaluated which patients undergo a breast reconstruction and if they have a different current QoL in comparison with women without a breast reconstruction. Methods: All women who underwent a curative mastectomy between 1999-2009 were included. Patients were sent a questionnaire existing of the recently developed, validated and breast reconstruction specific BREAST-Q, additional questions from the EORTC QLQ C-30 and BR-23 and questions concerning demographical features and comorbidities. 143 patients completed the questionnaire (54%), of whom 109 underwent a mastectomy and 43 a mastectomy and breast reconstruction. The average age of the study population was 66 years, the average follow-up after mastectomy was 6.8 years. Results: Age was the only independent predictor for undergoing a breast reconstruction (OR 3.0; 95% CI 1.1-8.4). Multivariate analysis showed that breast reconstruction is an independent predictor for a higher ‘Satisfaction With Outcome’ (SWO) and ‘Sexual Well-Being’ (SxWB). Mastectomy was an independent predictor for ‘Physical Well-Being’ (PWB) (all P<0.01). Furthermore, breast reconstruction showed a trend for a higher outcome in ‘Psychosicial Well-Being’ (PsWB) (P=0.07). Radiation therapy is an independent predictor for a lower PWB (P=0.03), a widowed marital status and obesity are independent predictors for a lower SxWB (P=0.03 and P=0.02). Conclusion: Age is the only independent predictor for undergoing a breast reconstruction. Undergoing a breast reconstruction does influence the QoL. Furthermore, radiation therapy, a widowed marital state and obesity are important predictors for a lower QoL. These results will enable us to further refine patient education concerning breast reconstruction.
| Item Type: | Thesis (Thesis) |
|---|---|
| Supervisor name: | Facultair begeleider and Jansen, Dr. L. |
| Supervisor name: | Externe begeleider and Vrouenraets, Dr. B.C. and Sint Lucas Andreas Ziekenhuis te Amsterdam and Afdeling Heelkunde |
| Faculty: | Medical Sciences |
| Date Deposited: | 25 Jun 2020 10:49 |
| Last Modified: | 25 Jun 2020 10:49 |
| URI: | https://umcg.studenttheses.ub.rug.nl/id/eprint/1042 |
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